| 64 | Jingyi Li (WF) def. Alisha Hussain (ECU) 4-6, 6-3, 6-1 |
| 32 | Marina Skegro (CSU) def. Jingyi Li (WF) 2-6, 6-4, 6-4 |
| 32 | Gina Dittmann (NCSU) def. Brooke Killingsworth (WF) 6-4, 6-3 |
| 32 | Anna Brylin (WF) def. Karolina Berankova (DUKE) 6-2, 6-3 |
| 32 | Eleni Louka (CLEM) def. Whitley Pate (WF) 6-3, 6-4 |
| 32 | Casie Wooten (WF) def. Anna Babayan (CCU) 6-0, 6-2 |
| 32 | Nevena Carton (WF) def. Kennedy Hill (NCCU) 6-1, 6-0 |
| 16 | Maddie Lynch (WF) def. Dasha Osadova (WCU) 6-4, 6-3 |
| 16 | Anna Brylin (WF) def. Sara Snyder (FURMAN) 6-4, 6-2 |
| 16 | Casie Wooten (WF) def. Cristina Mayorova (CLEM) 6-2, 6-2 |
| 16 | Nevena Carton (WF) def. Elise Mills (SC) 4-6, 6-4, 6-3 |
| 16 | Mia Ahmad (WF) def. Shauna Galvin (ELON) 6-1, 6-3 |
| C | Brooke Killingsworth (WF) def. Jenna Thompson (CLEM) 6-4, 6-2 |
| C | Luca Vocke (FURMAN) def. Whitley Pate (WF) 6-4, 7-6 (7-3) |
| C | Brooke Killingsworth (WF) def. Lindsay Zink (UNC) 7-6 (7-4), 6-2 |
| qf | Maddie Lynch (WF) def. Brianna Wilbur (WOFF) 6-1, 6-4 |
| qf | Ayana Akli (SC) def. Anna Brylin (WF) 6-4, 6-7 (4-7), 6-4 |
| qf | Casie Wooten (WF) def. Sophie Abrams (NCSU) 6-0, 6-1 |
| qf | Cameron Morra (DUKE) def. Nevena Carton (WF) 7-5, 6-0 |
| qf | Andrea Redondo (WCU) def. Mia Ahmad (WF) 6-2, 6-1 |
| sf | Maddie Lynch (WF) def. Zoe Huffman (UNCW) 6-4, 6-4 |
| fi | Maddie Lynch (WF) def. Zoe Huffman (UNCW) 6-4, 4-4 |
| sf | Cameron Morra (DUKE) def. Casie Wooten (WF) 6-4, 7-6 (7-4) |
| C | Katie Codd (DUKE) def. Brooke Killingsworth (WF) retired |